Complex workflows, simple digital health solutions
Real-world insights
Having that interface [between our EHR system and Exact Sciences Laboratories] is a dramatic benefit to be able to track down the discrete information of the screening.1
Drive actionable insights
Build a strong foundation for screening success
EHR integration simplifies ordering and result reporting, reduces friction, and creates better experiences across your health system — for both providers and patients.
We integrate with 10+ EHR platforms across our portfolio of tests including:
- Cologuard: Scalable integrations that simplify workflows and speed up patient care. Workflow optimizations, eligible patients, rescreens, other EHRs (Trisha confirm)
- Cancerguard: We work with Aura, HL7, and other platforms for easier ordering and resulting
- Precision oncology: Streamlined test ordering, results reporting, and workflow optimization

Identify core enhancements
Turn data into action
Measure and report
Advance your health system with smarter integration and workflow optimizations.
Optimize your technology investment
Our dedicated digital health teams are here to support you with:
- EHR integration project managers for seamless system integration
- Digital health strategists for ongoing strategic support and workflow improvement
A case study for data-driven success
Real-world examples
References
Important Information about the Cologuard products
Indications for Use
The Cologuard® and Cologuard Plus™ tests are intended for the qualitative detection of colorectal neoplasia associated DNA markers and for the presence of occult hemoglobin in human stool. A positive result may indicate the presence of colorectal cancer (CRC) or advanced adenoma (AA)/advanced precancerous lesions (APL) and should be followed by a colonoscopy. The Cologuard test and Cologuard Plus test are indicated to screen adults of either sex, 45 years or older, who are at average risk for CRC. These tests are not a replacement for diagnostic colonoscopy or surveillance colonoscopy in high-risk individuals.
Contraindications
The Cologuard products are not for high-risk individuals, including patients who have the following:
- a personal history of colorectal cancer or adenomas
- a positive result from another colorectal cancer screening method within that test's recommended screening interval
- have been diagnosed with a condition associated with high risk for colorectal cancer such as inflammatory bowel disease (IBD), chronic ulcerative colitis (UC), Crohn’s disease
- have a first-degree family history of colorectal cancer, or certain hereditary syndromes
Patients should talk to a healthcare provider if any of these situations apply.
Warnings and Precautions
All positive results should be referred to colonoscopy.
The Cologuard products may produce false positive and false negative results. A false positive result occurs when a result is positive, even though a colonoscopy will not find CRC or APL. A false negative result occurs when a result is negative, even when a colonoscopy identifies APL or CRC.
A negative result does not guarantee the absence of colorectal cancer or advanced adenoma. Following a negative result, patients should continue participating in a screening program at an interval and with a method appropriate for the individual patient. Performance when used for repeat testing has not been established.
Refer to the Cologuard test Clinician Brochure or the Cologuard Plus test Clinician Brochure for additional information about the benefits and risks of using each version of the Cologuard product for CRC screening.
Rx only.